Swine Health - PRRS
Year 2 funding support for the PRRS Host Genetics Consortium: A proposal to study the role of host genetics and resistance to PRRSV
June 22, 2010By Raymond R. Rowland
The PHGC represents the first-of-its-kind approach to food animal infectious disease research. The NPB, PRRS CAP, ARS, USDA AFRI, private companies, and universities have come together to conduct...
Swine Health - PRRS
Vaccination of pigs with alphavirus replicon particles expressing PRRSV ORF 3, 4, 5 and 6
June 21, 2010By D.L. Hank Harris
The objective of this project was to evaluate alphavirus replicon particles (RP) expressing various PRRSV proteins as vaccine candidates. Previous work has identified the minor structural...
Swine Health - PRRS
Development of a rapid, swine-specific test to simultaneously detect multiple immune proteins (cytokines) affected by PRRSV infection
June 18, 2010By Jane Christopher-Hennings
Cytokines are small secreted proteins which mediate and regulate immunity to viral infections in swine and other species. Evidence suggests that PRRSV does not induce early, effective...
Swine Health - PRRS
Sequencing, Cloning and Characterization of a 2007 Vietnam PRRSV isolate
June 17, 2010By Kay S. Faaberg
Epidemics of severe swine disease, termed “Porcine High Fever Disease (PHFD)”, continue to be reported in...
Swine Health - PRRS
Genetic and antigenic characterization of a recent PRRSV isolate
May 30, 2010By Tanja Opriessnig
Porcine reproductive and respiratory syndrome virus (PRRSV) NC16845 was isolated from porcine tissue submitted to the Iowa State University Veterinary Diagnostic Laboratory in 2006. The isolate...
Swine Health - PRRS
Evaluation of adjuvants at the mucosal area for the development of innovative mucosal vaccine against PRRS
April 29, 2010By Renukaradhya Gourapura
Porcine Reproductive and Respiratory Syndrome (PRRS) is a chronic and economically important viral disease of pigs. Currently available PRRS virus (PRRSV) vaccines have been administered systemically...
Swine Health - PRRS
Identifying PRRSV structural components that activate regulatory T cells and diminish protective immunity
April 26, 2010By Tanya LeRoith
This study was designed to test the hypothesis that certain structural components of PRRSV drive the activation of regulatory T cells (Tregs). Activating these T cells would thereby diminish the...
Swine Health - PRRS
Role of All of the PRRSV Glycoproteins in Protective Immune Response
March 4, 2010By Asit Pattnaik
Porcine reproductive and respiratory syndrome (PRRS) caused by PRRS virus (PRRSV) is of major economic significance to swine industry in the U.S.A. and worldwide. Currently, there is no effective...
Swine Health - PRRS
Optimization of the PRRSV antibody ELISA for use in oral fluid-based surveillance
February 4, 2010By Jeffrey Zimmerman
PRRSV, M. hyopneumoniae, influenza, PCV2, and other endemic pathogens continue to cause significant economic losses to U.S. swine producers. In part, the disease status quo is maintained by the...
Swine Health - PRRS
Induction of Cross-Protective Immunity without Exposure to Live PRRSV
December 23, 2009By Luis Enjuanes
Explanation of the objectives. The development of more efficacious vaccines was one of the objectives for NPB 2008 funding. The work reported here is focused on the engineering of a modified live...
