Swine Health - PRRS
Structural characterization of the PRRSv glycan shield
July 15, 2011By Michael P. Murtaugh
Knowing the composition and structure of PRRSV is an important prerequisite for development of immunological prevention and control strategies, just as knowing what a spark plug looks like is...
Swine Health - PRRS
Subverting the function of PRRSV nucleocapsid protein for innovative vaccine design
June 26, 2011By Julian Hiscox
Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the major virus threats facing the swine industry in the USA and worldwide. Whilst the introduction of vaccines has been...
Swine Health - PRRS
Gene expression in lymph nodes of PRRSV-infected pigs
June 17, 2011By Laura Miller
The aim of this study was to acquire a better understanding of PRRS disease through a deeper knowledge of gene expression changes that occur in pulmonary lymph nodes during acute comparative porcine...
Swine Health - PRRS
Molecular Structures of PRRSV that Contribute to PRRSV Protective Immunity
April 19, 2011By Asit Pattnaik
Porcine reproductive and respiratory syndrome (PRRS) caused by PRRS virus (PRRSV) is of major economic significance to swine industry. There is no effective vaccine currently available to combat...
Swine Health - PRRS
Molecular Identification of Type I Interferon Antagonistic Components of PRRSV Proteins
February 25, 2011By Kay S. Faaberg
Basic knowledge of PRRSV infections and clues to successful PRRSV control have led to the discovery of type 1 interferon inhibition by several viral strains, which is purported to be instrumental in...
Swine Health - PRRS
An assessment of air filtration for reducing the risk of PRRSV infection in large breeding herds in swine dense regions
February 16, 2011By Scott A. Dee
As the US swine industry moves towards regional control and elimination of PRRSV, a critical component is the ability to reduce the risk of the airborne spread of the virus between herds....
Swine Health - PRRS
Application of FTA based technology for the collection and transport of clinical samples to detect PRRSV by RT-PCR
February 1, 2011By Montse Torremorell
The ability for producers to succeed depends in part, on their ability to rapidly respond to emerging and existing disease challenges. Submission of fresh samples to diagnostic laboratories in a...
Swine Health - PRRS
Mechanisms of Failed Protection Against PRRS in Sow Herds
September 21, 2010By Michael Murtaugh
Serum inoculation of gilts with on-farm isolates is used to protect endemically infected sow herds against reproductive PRRS. However, outbreaks still occur in which the offending virus is...
Swine Health - PRRS
Development of a modified live vaccine against PRRSV with optimal DIVA marker potential
August 2, 2010By Fernando Osorio
Work in our laboratories is exclusively oriented towards the development of a new generation of PRRSV vaccines that would confer broad protection. We work, through different basic and applied...
Swine Health - PRRS
Subverting the function of PRRSV nucleocapsid protein for innovative vaccine design.
July 13, 2010By Julian Hiscox
This research proposal was conceived as a three-year project, with this report encompassing Year 1. PRRSV is recognized as one of the major virus threats facing the swine industry in the...