Swine Health - PRRS
Estimating the infectious dose for transmission of PRRSV by aerosol exposure
August 11, 2009By Jeffrey Zimmerman
The objective of this research was to quantify the likelihood of PRRSV transmission via aerosols as a function of exposure dose. This information is important because it reveals the process by which...
Swine Health - PRRS
Identification of Type I Interferon Antagonists of PRRSV Viral Structural Proteins
August 3, 2009By Kay S. Faaberg
PRRSV is an important swine pathogen and infections caused by this virus have not been efficiently controlled. This is in part due to the lack of knowledge about the insufficient swine immune...
Swine Health - PRRS
Understanding the role of the regulatory immune response in porcine reproductive and respiratory syndrome virus persistence
July 30, 2009By Tanya LeRoith
This study addressed an important question in the mechanism of persistence and immune suppression by PRRSV. PRRSV persistence currently is a major problem in the field. However, the mechanism by...
Swine Health - PRRS
Elimination of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) from semen: “On Farm” Mechanical and Antiviral Methods
June 12, 2009By Jane Christopher-Hennings
The long-term objective of this research is to provide a “PRRSV-free semen supply for artificial insemination (AI)”. Therefore, a 2-pronged approach to “on farm” methods that...
Swine Health - PRRS
Rational Design of a New Generation of PRRSV Differential (Marker) Vaccines (Renewal, 2007)
May 13, 2009By Fernando Osorio
Both industry and scientific experts alike agree in that an effective, broadly protective vaccine against PRRS is a very important tool to help in the control of this disease. Our laboratory pursues...
Swine Health - PRRS
Predictors of response and genetic resistance/susceptibility in pigs to infection with Porcine Reproductive and Respiratory Syndrome virus
May 4, 2009By Donald G. Levis PhD
Porcine reproductive and respiratory syndrome virus (PRRSV) has caused devastating losses to swine herds on a worldwide basis. It has been estimated that PRRSV costs the United States pork industry...
Swine Health - PRRS
Immunogenicity and potency of PRRS MLV vaccines with and without interferon-alpha suppressing capacity
March 2, 2009By Federico A. Zuckermann
Interferon (IFN)-alpha is the most important anti-viral substance produced by mammalian cells in response to a viral infection. Accordingly, the production of IFN-alpha by an animal during a viral...
Swine Health - PRRS
Use of a production region model to evaluate biosecurity protocol efficacy for reducing the risk of PRRSV and Mycoplasma hyopneumoniae spread between farms
February 12, 2009By Scott Dee
The purpose of this 2-year project was to investigate the transmission of PRRSV and Mycoplasma hyopneumoniae (M hyo) by aerosols, the meteorological conditions associated with this route of spread...
Swine Health - PRRS
Development of a New Generation of Antisense Antiviral Drug against PRRSV
January 23, 2009By Yan-Jin Zhang
This project has explored a novel class of antiviral drugs to suppress PRRSV replication. These drugs were designed on the basis of PRRSV genomic sequences. Their specific binding to the virus genome...
Swine Health - PRRS
Assessing the use of biofilters and antimicrobial filters to reduce the excretion of PRRS virus into the environment
January 22, 2009By Scott Dee
As area-based PRRSV control and eradication programs move forward, the ability to minimize the risk of PRRSV-excretion into the environment from infected populations becomes important. This study...
