Swine Health - PRRS
Implementation of an integrated mapping service to support regional control and elimination of PRRS virus
November 6, 2012By Robert B. Morrison
There are approximately 20 regional PRRS projects in the United States in various stages of progress. Each coordinator has their own...
Swine Health - PRRS
Mechanism of PRRSV inhibition of interferon-mediated antiviral response
November 3, 2012By Yan-Jin Zhang
The objective of this project was to study the effect of PRRSV infection on interferon (IFN) signaling and determine the mechanism of the effect. Type I IFNs, such as IFN-α and -β, are...
Swine Health - PRRS
Identification of the viral protein that mediates PRRSV attachment to the sialoadhesin receptor on primary macrophages, and determination of the minimal epitope on this protein needed for receptor interaction.
June 7, 2012By Peter Delputte
Protection of pigs towards PRRSV infection mainly depends on the presence of antibodies in the pig that block virus infection of macrophages. Those neutralizing antibodies are directed against the...
Swine Health - PRRS
Identification of conserved T-cell epitopes contained in the non-structural genes of PRRSV which contribute to broad protective immunity
April 16, 2012By Fernando Osorio
Effective vaccine protection against infection by any of the multiple PRRSV strains that circulate in the field is of major...
Swine Health - PRRS
An evaluation of back-drafting of non-filtered air as a source of PRRSV infection to pigs housed in filtered facilities and whether selected intervention strategies can reduce this risk
April 9, 2012By Scott A. Dee
The objectives of this study were to demonstrate that the risk of PRRSV-contaminated aerosols entering a facility via retrograde air is a true risk though unfiltered points (i.e. idle fans); to...
Swine Health - PRRS
Understanding the effect of concurrent PCV2a or PCV2b infection on the evolution of the PRRSV during serial passage in pigs
April 3, 2012By Tanja Opriessnig
Porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus type 2 (PCV2) infections are among the most important swine viruses facing the industry today. Although vaccines...
Swine Health - PRRS
Comparison of early immune responses of pigs which are genetically PRRS resistant/tolerant using a swine-specific immune protein (cytokine) multiplex assay
March 27, 2012By Joan K. Lunney
PRRS causes major economic losses to the US pig industry, as reflected in debilitating respiratory syndromes, major reproductive losses and unthrifty piglets; economic losses were calculated to...
Swine Health - PRRS
PRRSV Modulation of the Porcine Antibody Repertoire
January 19, 2012By Michael P. Murtaugh
Antibody responses play a crucial role in defense against many viral diseases, and knowledge of critical functions can be used to monitor and...
Swine Health - PRRS
Development of novel mucosal vaccines for the control of PRRSV outbreaks
November 29, 2011By Renukaradhya Gourapura
Porcine Reproductive and Respiratory Syndrome (PRRS) is an economically important chronic viral disease of pigs. Available PRRS virus (PRRSV) vaccines are not completely protective to control the...
Swine Health - PRRS
Development of diagnostic assays for detecting PRRSV infection using oral fluid samples as an alternative to serum-based assays
July 26, 2011By Ying Fang
Currently, diagnosis of PRRSV infection is by virus antigen, nucleic acid or antibody detection in serum samples. Thus, serum is the standard sample for diagnostic evaluation. However,...
