Salmonella, E. coli and Yersinia are bacteria that can cause foodborne illness in humans. These bacteria can be found in the intestinal tract of pigs, therefore methods are sought to rid these bacteria from pigs before slaughter. We previously demonstrated that an experimental chlorate product could reduce Salmonella and E. coli in pigs. In the present study, certain nitrocompounds were able to kill Salmonella, E. coli and Yersinia in the laboratory and when fed to swine, markedly enhanced the bacterial-killing capacity of the chlorate product. Subject to regulatory approval, it is possible that these compounds may be developed into feed additives that can be fed prior to slaughter to rid bacterial pathogens from swine.