The oregano oil product evaluated did not enhance nursery pig performance or influence the development of antimicrobial resistance to the panel of antibiotics used to screen resistance. While a high level of multiple antimicrobial resistance was apparent at the beginning of the study, decreases in the level of resistance to several of the antibiotics was an attribute of all the dietary treatments. Therefore, the oregano oil product demonstrated no apparent benefit over Carbadox or the Control diet in modulating antimicrobial resistance. The less than superb performance obtained from feeding the oregano oil product appears to be a function of depressed feed intake based on the intake and feed efficiency data. The strongly aromatic nature of the oregano oil product most likely discouraged consumption of the diet resulting in the poor pig performance.