Swine Health - PRRS
The contribution of adaptive immunity to Porcine Reproductive and Respiratory Syndrome virus infection
January 5, 2015By Melinda Wilkerson
Objectives: The purpose of our studies was to understand how adaptive immunity contributes to the susceptibility of nursery-age piglets to...
Swine Health - Foreign Animal Disease
Identification of Protective Antigens of African Swine Fever Virus
January 2, 2015By Daniel Rock
African swine fever (ASF) is arguably the most significant emerging disease threat for the swine industry worldwide. Devastating ASF...
Swine Health - PRRS
Development of PRRS virus-like-particles containing nanoparticle vaccine and its evaluation in pigs
December 1, 2014By Renukaradhya Gourapura
Porcine Reproductive and Respiratory Syndrome (PRRS) is a chronic and economically important viral disease of pigs. Currently used PRRS virus (PRRSV) vaccines have failed to completely protect...
Swine Health - PRRS
Rational design of a broadly protective vaccine against porcine reproductive and respiratory syndrome virus
November 14, 2014By Hiep Vu
Current PRRS vaccines are not adequately effective for control and eradication of PRRS. The main limitation of the current PRRS vaccines is their sub-optimal coverage against divergent PRRSV strains...
Swine Health - PRRS
Defining a Novel Structural Component of Porcine Reproductive and Respiratory Syndrome Virus and its Role in Disease Pathogenesis
November 13, 2014By Kay S. Faaberg
The objective of this project was to characterize the makeup of nsp2, shown to be a new structural component of the PRRSV virion. Radiolabelled nsp2 protein, in the absence or presence of...
Swine Health - General Disease
Molecular Characterization and Protective/Diagnostic Application of the Capsular Polysaccharide of Haemophilus parasuis
November 5, 2014By Thomas Inzana
Haemophilus parasuis (Hps) is an important swine pathogen that can decimate a swine herd in less than 72 hours. Although this bacterium has devastating effects on pork producing facilities,...
Swine Health - PRRS
Impact of pig farm density on incidence of PRRS in a cohort of sow herds
October 1, 2014By Robert B. Morrison
This project was designed to measure the incidence of PRRS infection in a cohort of US sow herds. Additionally, it sought to conduct a risk assessment based on the density of swine farms around...
Swine Health - PRRS
Further development of an integrated mapping service to support regional control & elimination of PRRS virus
October 1, 2014By Robert B. Morrison
There are approximately 20 regional PRRS projects in the United States in various stages of progress. Each coordinator has their own approach to the challenges of mapping the region, many depending...
Swine Health - PRRS
Viral structural components that enable vaccine-induced protective immunity against contemporary high morbidity and high mortality PRRS virus
September 18, 2014By Federico A. Zuckermann
The production of interferon (IFN)- by an animal in response to a viral infection is known to be a principal determinant of the animal’s ability to fight the infection. In addition, this...
Swine Health - General Disease
Advances in Vaccine Design: Developing A Cross-conserved Influenza Vaccine for Swine
July 28, 2014By Anne De Groot
The overall goal of this project was to implement the innovative iVAX suite of immunoinformatics vaccine design tools that have been extensively validated in pre-clinical studies of human...
