Swine Health - Foreign Animal Disease Archives - Pork Checkoff

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Swine Health
Classical Swine Fever PCR Negative Cohort Study

Partnering to expand testing capacities, support further evaluation and validation of two commercially available CSF PCR assays, and enhance preparedness across the NAHLN.

Swine Health
Assessing the feasibility of the mRNA vaccine technology for use against ASF

In this study, we aim to explore the potential of mRNA vaccine technology for the development of a subunit vaccine against ASFV. For this pilot project, we focused on assessing the immunogenicity of mRNA vaccines containing four well-characterized ASFV antigens: p32, p54, C-type lectin, and CD2v. Each of these antigens plays a distinct role in the viral lifecycle.

Swine Health
Evaluation of the performance of ELISA for ASF-antibodies detection and its potential use in the US swine industry

The objective of this study was to estimate and compare the diagnostic performance of a novel indirect enzyme-linked immunosorbent assay (iELISA) for ASF serum antibodies (iELISA), developed by Innoceleris Ames, IA, USA and produced and commercialized by Tetracore (Rockville, MD, USA), and the VetAlert™ ASFV DNA Test Kit (qPCR, Tetracore) in both serum and oral fluid (OF) samples collected on farms in Vietnam.

Swine Health - Foreign Animal Disease
Risk Assessment for Importing Non-Animal-Origin Feed and Ingredients from ASFV-Endemic Regions
Currently, there are industry wide concerns over African swine fever virus (ASFV) entry from a variety of different sources, including imported ingredients from ASFV positive countries. Data...
Swine Health - Foreign Animal Disease
Understanding the Survivability and Infectivity of African Swine Fever Virus in Various Environments
African swine fever (ASF) is the most significant foreign animal disease threat to the US pork industry. ASF virus (ASFV) not only causes high case fatality rates of infected pigs but is a...
Swine Health - Foreign Animal Disease
Identification of Protective Antigens of African Swine Fever Virus
African swine fever (ASF) is an acute viral disease of domestic swine with mortality rates approaching 100%. Currently endemic in extensive regions of Eurasia, ASF is “out of Africa”...
Swine Health - Foreign Animal Disease
Evaluation of Lyophilization on Efficacy of African Swine Fever Vaccine Candidate ASFV-G-ΔI177L
Currently there is no commercialized vaccine for African swine fever (ASF). One of the most promising candidates to date is the highly effective and safe live attenuated vaccine candidate...
Swine Health - Foreign Animal Disease
Factors to Consider in a Potential Eradication Plan for African Swine Fever in the United States: A White Paper
This white paper presents factors to consider and potential approaches for developing an eradication plan for African swine fever (ASF) should it become established in the United States. The white...
Swine Health
An African Swine Fever (ASF) positive cohort study:  Validating various PCR tests and sample types for African Swine Fever Virus (ASFV) detection in boars; and determining the possibility of transmission via artificial insemination

The first study using experimentally ASFV inoculated adult, commercial boars to determine which sample types and PCR procedures were optimum in detecting ASFV in boars and gilts. Additionally, it proved that insemination of ASFV infected semen to naïve gilts resulted in transmission of the virus.

Swine Health
Evaluation of meat juice and muscle swabs using OIE-approved real time polymerase chain reaction (RT-PCR) from swine with clinically compatible signs of ASF in Ugandan slaughterhouses

This research project assessed the African swine fever virus’s (ASFV) nucleic acid detection in slaughter expedient samples: diaphragm meat juice, diaphragm muscle swab, spleen, and spleen swab.

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