Swine Health - PRRS
Pork Checkoff Research
Research is at the heart of the National Pork Board’s mission and is funded by your Pork Checkoff dollars. Research is administered in all areas of pork production, processing, and human nutrition to develop a higher quality and more profitable product in the competitive meat protein market.
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Swine Health - PRRS
Mechanism of Antibody-Mediated Neutralization of PRRSV
One of the challenges in developing effective vaccines for PRRSV is the limited understanding of how neutralizing antibody inhibits PRRSV replication, and how variation in PRRSV leads to escape from...
Swine Health - PRRS
Epitope Inclusion: Enhancing porcine reproductive and respiratory syndrome virus (PRRSv) vaccine cross-protective efficacy
Producers need better vaccines for controlling disease and spread associated with PRRSv infection. This has been an extremely different task because the face of PRRSv is constantly changing making an...
Swine Health - PRRS
Characterization of high passages of an interferon-inducing PRRSV strain
As stated in the contract, we require an industry summary of the project, suitable for immediate public release by the Board. The purpose of the industry summary is to provide producers...
Swine Health - PRRS
Determination of the PRRSV minor glycoproteins contribution to antigenicity and protection
Porcine reproductive and respiratory syndrome virus (PRRSV) has been the most significant disease affecting swine in the U.S. for decades. Contemporary epidemiological methods rely on sequencing of...
Swine Health - PRRS
Development of a Novel Self-Propagating PRSSV-VSV G Hybrid Replicon as a Vector for Inducing Broad PRRSV Protection
Throughout successive cycles of Pork Check-off funding, our laboratories (Pattnaik’s and Osorio’s labs) have consistently produced new and fundamental information on: (i) the...
Swine Health - PRRS
Development of on-farm PRRSV surveillance guidelines for the modern pork industry
Oral fluids (OF) are a convenient surveillance sample because they (1) are easily collected by a single person; (2) can be collected frequently without stress to pigs or people; and (3) provide...
Swine Health - PRRS
Evaluation of immunodominant B- and T-cell epitopes as inducers of protective immunity against porcine reproductive and respiratory syndrome virus
Since its emergence in domestic pigs in the late 1980’s, porcine reproductive and respiratory syndrome virus (PRRSV) has caused significant economic losses to swine producers worldwide. A...
Swine Health - PRRS
The effect of PRRSv infection on the thymus – a source of immune dysregulation?
PRRSv infection has been shown to cause an acute lymphopenia (loss of cells in the blood), lymphadenopathy (increased size of lymph nodes due to increased cell numbers) and thymic atrophy (decreased...
Swine Health - PRRS
Use of interferon alpha as an immunomodulator and metaphylactic therapeutic during PRRSV outbreaks
The host response to virus infection begins almost immediately with recognition of virus by host cells leading to the production of antiviral substances such as interferons. One interferon,...
