Swine Health - PRRS
Rational Design of a New Generation of PRRSV Differential (Marker) Vaccines (Renewal Summer 2006)
June 24, 2008By Fernando Osorio
This project is based on two main premises: 1) the conviction that the use of vaccines will always be a cost-efficient method and the preferred approach to control PRRSV infections, and 2) the notion...
Swine Health - PRRS
Exploring PRRS virus GP5 peptides for protective cross-reactive T cellepitopes
June 16, 2008By Carol Wyatt
Current vaccines have not met the needs of producers who want to control and eliminate PRRS. Development of vaccines that elicit protective anti-viral immune responses requires identification of...
Swine Health - PRRS
Enhancement of in vitro replication efficiency of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) in MARC-145 cell line
June 4, 2008By Frederick Leung
Porcine Reproductive and Respiratory Syndrome (PRRS) affects porcine industry globally and brings a significant economic loss in the agricultural sector. It is reported that both European and North...
Swine Health - PRRS
Development of protein based ELISA for the rapid strain specific identification of PRRSV and responding to novel emerging variants.
May 30, 2008By Julian Hiscox
The aim of this project was to develop and evaluate diagnostic reagents, tools and methodologies to identify both generic and specific strains of PRRSV as well as future proofing this technology for...
Swine Health - PRRS
Identification of a peptide sequence in nsp2 that can function as a deletion marker for the differentiation of vaccinated from naturally infected pigs
May 27, 2008By Raymond R. Rowland
The implementation of an effective control plan for PRRS will require safe and effective vaccines. Future modified live virus (MLV) vaccines will require a mechanism that can be used to 1) identify...
Swine Health - PRRS
Development of stable cell lines permissive for PRRSV replication and production
May 23, 2008By Dongwan Yoo
PRRS virus (PRRSV) infects only a specific line of simian cells in culture for productive infection. The use of these cells for vaccine development is patent-protected, which severely hampers the...
Swine Health - PRRS
In vivo evaluation of genetic markers in the nsp2 region of PRRSV: Implications for future recombinant marker vaccine development
May 15, 2008By Ying Fang
Porcine reproductive and respiratory syndrome (PRRS) virus (PRRSV) continues to be a major problem to the pork industry worldwide. The limitations offered by current PRRSV vaccines require the...
Swine Health - PRRS
An Industry Education Program for Understanding the Risk Factors Associated with PRRSv Breaks in Negative or Naïve Breeding Herds
May 5, 2008By Derald Holtkamp
Swine Health - PRRS
Global Gene Expression Profiling of PRRSV-infected Alveolar Macrophages
April 30, 2008By John Neill
This study examined the effect of porcine reproductive and respiratory virus (PRRSV) on how genes are expressed in porcine alveolar macrophages (PAMs). PAMs were chosen for this study because they...
Swine Health - PRRS
PRRSV infection of pig macrophages
February 19, 2008By William Cafruny
A. Objectives. The objective of this small grant were to was to investigate the regulation of PRRSV infection in cultured pig macrophages. The purpose of the work was to learn more about how PRRSV...
