Swine Health - General Disease
Understanding if porcine circovirus type 2 strain differences explain the recent Canadian outbreak
June 25, 2008By Patrick Halbur
In 2004, a marked increase in the incidence and severity of porcine circovirus associated disease (PCVAD) was observed in eastern Canada. The severe outbreaks of PCVAD in Canada, followed by similar...
Swine Health - PRRS
Rational Design of a New Generation of PRRSV Differential (Marker) Vaccines (Renewal Summer 2006)
June 24, 2008By Fernando Osorio
This project is based on two main premises: 1) the conviction that the use of vaccines will always be a cost-efficient method and the preferred approach to control PRRSV infections, and 2) the notion...
Swine Health - PRRS
Exploring PRRS virus GP5 peptides for protective cross-reactive T cellepitopes
June 16, 2008By Carol Wyatt
Current vaccines have not met the needs of producers who want to control and eliminate PRRS. Development of vaccines that elicit protective anti-viral immune responses requires identification of...
Swine Health - PRRS
Enhancement of in vitro replication efficiency of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) in MARC-145 cell line
June 4, 2008By Frederick Leung
Porcine Reproductive and Respiratory Syndrome (PRRS) affects porcine industry globally and brings a significant economic loss in the agricultural sector. It is reported that both European and North...
Swine Health - General Disease
Development of a surveillance system to monitor the genetic variability and molecular epidemiology of swine bacterial pathogens
June 4, 2008By Simone Oliveira
The objective of this project was to develop a surveillance system to monitor the genetic variability and molecular epidemiology of swine bacterial pathogens. The specific aims of this projects were:...
Swine Health - PRRS
Development of protein based ELISA for the rapid strain specific identification of PRRSV and responding to novel emerging variants.
May 30, 2008By Julian Hiscox
The aim of this project was to develop and evaluate diagnostic reagents, tools and methodologies to identify both generic and specific strains of PRRSV as well as future proofing this technology for...
Swine Health - PRRS
Identification of a peptide sequence in nsp2 that can function as a deletion marker for the differentiation of vaccinated from naturally infected pigs
May 27, 2008By Raymond R. Rowland
The implementation of an effective control plan for PRRS will require safe and effective vaccines. Future modified live virus (MLV) vaccines will require a mechanism that can be used to 1) identify...
Swine Health - PRRS
Development of stable cell lines permissive for PRRSV replication and production
May 23, 2008By Dongwan Yoo
PRRS virus (PRRSV) infects only a specific line of simian cells in culture for productive infection. The use of these cells for vaccine development is patent-protected, which severely hampers the...
Swine Health - General Disease
Characterizing level of PCV type 2 virus in serum and expression of PMWS in different populations of pigs
May 19, 2008By Rodger Johnson
Selection for resistance to PCV2 virus is possible. It can be accomplished by serially scoring pigs for symptoms of PCVAD from 60 to 125 d of age, weighing pigs at these ages, and measuring serum...
Swine Health - PRRS
In vivo evaluation of genetic markers in the nsp2 region of PRRSV: Implications for future recombinant marker vaccine development
May 15, 2008By Ying Fang
Porcine reproductive and respiratory syndrome (PRRS) virus (PRRSV) continues to be a major problem to the pork industry worldwide. The limitations offered by current PRRSV vaccines require the...
