Swine Health - General Disease
Evaluation of pathogenesis of concurrent SIV and PCV2 infection in CD/CD pigs
The objectives of the project were to determine if 1) SIV infection (H1N1, not pandemic H1N1) could initiate...
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Swine Health - General Disease
The role of maternal antibody in determining PCV2 vaccine efficacy
Commercial PCV2 vaccines are remarkably effective in controlling PCVAD. However, there are still concerns regarding the appearance of what appears to be “vaccination failures”, which...
Swine Health - General Disease
Testing of a live enterotoxigenic E. coli vaccine candidate for its potential as a competitive exclusion probiotic for preventing colibacillosis in weaned pigs.
The bacterium Enterotoxigenic Escherichia coli (E. coli) is a major cause of post-weaning scours in weaned pigs, most frequently causing disease shortly after weaning. Currently no licensed vaccines...
Swine Health - General Disease
Development of a live attenuated vaccine against swine influenza by reverse genetics
Influenza A virus causes significant morbidity in swine, resulting in a substantial economic burden. Swine influenza virus also poses threat to public health, a prime example is the recent emerged...
Swine Health - PRRS
Role of All of the PRRSV Glycoproteins in Protective Immune Response
Porcine reproductive and respiratory syndrome (PRRS) caused by PRRS virus (PRRSV) is of major economic significance to swine industry in the U.S.A. and worldwide. Currently, there is no effective...
Swine Health - General Disease
Strategies to include STa antigen in vaccine development against porcine post-weaning diarrhea (PWD);
Enterotoxigenic Escherichia coli (ETEC) strains are a major cause of diarrhea disease in humans and farm animals. E. coli fimbriae or colonization factor antigens (CFAs) and enterotoxins including...
Swine Health - General Disease
Do capsid mutants with the PCV-2 genotype variations induce virulence differences in vitro and in vivo?
The porcine circovirus of type 2 (PCV-2) is involved in porcine circovirus diseases such as post-weaning multisystemic wasting syndrome (PMWS), reproduction disorders, porcine dermatitis and...
Swine Health - General Disease
Prevalence of slaughter house condemnation due to Erysipelothrix sp. and further characterization of isolates associated with these cases
The objective of this study was to confirm the presence and investigate the identity of Erysipelothrix spp. in condemned tissues obtained from a regional abattoir. Tissue specimens from 70 carcasses...
Swine Health - PRRS
Optimization of the PRRSV antibody ELISA for use in oral fluid-based surveillance
PRRSV, M. hyopneumoniae, influenza, PCV2, and other endemic pathogens continue to cause significant economic losses to U.S. swine producers. In part, the disease status quo is maintained by the...
Swine Health - General Disease
PCVAD Induced Immune Dysfunction
This project included a team of PCVAD researchers from KSU, ISU and SDSU who utilized a single set of experimentally infected pigs to address several important questions related to pathobiology,...
