Swine Health - PRRS
Use of interferon alpha as an immunomodulator and metaphylactic therapeutic during PRRSV outbreaks
January 14, 2016By Susan L. Brockmeier
The host response to virus infection begins almost immediately with recognition of virus by host cells leading to the production of antiviral substances such as interferons. One interferon,...
Swine Health - General Disease
Linking veterinary diagnostic laboratory submissions and corresponding PEDV test results to spatiotemporal mapping tools: the future of disease management, control and elimination
January 6, 2016By Rodger Main
Streamlined systems that link diagnostic submissions and corresponding test results to spatiotemporal disease management tools are needed to enhance US pork producers’ ability to proficiently...
Swine Health - PRRS
Determine the mechanisms of cross-protection against infection with a divergent porcine reproductive and respiratory virus strain
December 11, 2015By Hiep Vu
PRRS modified live virus (MLV) vaccines have been licensed for clinical administration for over 20 years. The vaccines confer solid protection against homologous PRRSV strains. However, the extent...
Swine Health - PRRS
Development of next generation sequencing methodology for full genome characterization of porcine reproductive and respiratory syndrome virus (PRRSV) from oral fluids and nasal swabs
September 23, 2015By Ben Hause
Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most significant swine diseases with near worldwide distribution. In the U.S., open reading frame 5 (ORF5) is commonly...
Swine Health - General Disease
Evaluation of diagnostic performance characteristics of commercially-available CSFV tests
August 15, 2015By Yaowalak Panyasing
Classical swine fever virus (CSFV) is endemic and circulates in many regions of the world; therefore, the potential re-emergence of CSFV is a continual risk. It is in the pork producers' best...
Swine Health - General Disease
Evaluation of two novel live attenuated swine influenza vaccines against newly emerging H3N2 virus infection and transmission
July 7, 2015By Yan Zhou
After the 2009 pandemic, variant H3N2 swine influenza viruses (H3N2v SIV) carrying genes from pandemic H1N1 emerged in pig farms. The objective of this study is to investigate whether the two live...
Swine Health - General Disease
Development of an Actinobacillus pleuropneumoniae (APP) oral fluid antibody ELISA based on the detection of antibodies to APP ApxIV toxin in oral fluid specimens
May 14, 2015By Jeffrey Zimmerman
Actinobacillus pleuropneumoniae (APP) is a significant respiratory pathogen of swine, causing acute death in finishing pigs and adding significant treatment costs to the...
Swine Health - General Disease
Defining PEDV maternal humoral immunity and correlates of neonatal protection
April 29, 2015By Luis Gimenez-Lirola
Through the proposed approach we tried to the answers PEDV serology questions from the field regarding the association between maternal anti-PEDV antibody and protection of neonates against PEDV. It...
Swine Health - General Disease
Age related changes in the intestinal microbiome protect neonatal piglets from Clostridium difficile infection
April 22, 2015By Nancy Cornick
Clostridium difficile has been recognized as a significant cause of illness in neonatal pigs, but is not encountered in piglets older than 1 week of age. We hypothesized that this age related...
Swine Health - General Disease
Live-animal assay for identifying correlates of protection/cross-protection for intranasal swine influenza virus vaccines
April 14, 2015By Crystal Loving
The majority of vaccines currently available for the prevention of influenza A virus (IAV) in swine are formulated as whole-inactivated...
