Swine Health - General Disease
Assessment of viral load in clinical and subclinical pigs naturally infected with the novel PCV2b: implications for the control & prevention of PMWS/PCVD
June 29, 2007By John Harding
After its discovery in the mid-1990’s postweaning multisystemic wasting syndrome (PMWS) was noted only sporadically in North America for about a decade. However, since late 2004, the porcine...
Swine Health - PRRS
Investigation of factors impacting the rate of PRRSV transmission in nursery and finisher pig flows and assessment of transmission rate and timing on economic performance
June 18, 2007By Locke Karriker
As stated in the contract, we require a lay interpretation of the project, suitable for public release by the Board. Please include contact information, should the public want to contact you...
Swine Health - PRRS
Development of a Broadly Protective PRRS Vaccine
May 27, 2007By Gregory Tobin
The current vaccines against PRRSV protect pigs exposed to the strain used to make the vaccine, but not to the many field strains that herds encounter. The lack of protection against heterologous...
Swine Health - General Disease
Expanding the immune toolkit for assessing pig health and improving swine disease and vaccine studies
May 8, 2007By Joan K. Lunney
Swine disease and vaccine research will be advanced by the development of sophisticated tools to measure swine antibodies or immunoglobulins (Igs). Swine produce antibodies, or Igs, in response to...
Swine Health - PRRS
Development of cost-efficient herd testing protocols based on testing of pooled samples using ELISA
April 2, 2007By Claudia Munoz-Zanai
The objective of this study was to evaluate the feasibility of using pooled serum samples for detection of PRRSV-infected sow herds by ELISA. In order to achieve this objective, 113 true positive...
Swine Health - PRRS
Evaluation of a novel anti-idiotype vaccine against PRRSV infection
March 27, 2007By Jeffrey Zimmerman
The primary objective of this project was to test a PRRS vaccine based on a PRRSV anti-idiotypic antibody. Subsequent to the primary objective, the intent was to determine whether effective vaccines...
Swine Health - PRRS
Physical Characterization of the PRRSV Virion
March 23, 2007By Michael Murtaugh
The research here shows that PRRSV grows in cells as a population of viruses with the same shape, the same RNA molecules, and the same protein composition. There was no evidence for multiple forms...
Swine Health - PRRS
Mechanisms of Failed Protection Against PRRS in Sow Herds
February 28, 2007By Michael Murtaugh
We have established a set of standard protocols and reagents for whole genome PRRSV sequencing and assembly. Phylogenetic comparisons amongst 10 pairs of homologous strains confirmed several regions...
Swine Health - General Disease
Evaluation of diagnostic assays for Mycoplasma hyopneumoniae: Their potential role in eradication success
February 20, 2007By Eileen Thacker
Respiratory disease induced by Mycoplasma hyopneumoniae (Mhyo) is a problem recognized by the swine industry world-wide. Due to the significant production costs associated with Mhyo-induced...
Swine Health - PRRS
Investigation into the ability of the anti-idiotype to block PRRS virus infection and characterization of a putative receptor on MARC-145 cells and porcine alveolar macrophages
November 25, 2006By Jeffrey Zimmerman
PRRS is the most costly disease U.S. swine producers confront and little progress has been made in recent years to improve the situation. Prevention and control of PRRS has been difficult, in part...
