Swine Health - General Disease
Determination of the amount of PCV2 needed for intrauterine transmission and assessment of effect of PCV2 exposure (natural and vaccine) prior to insemination
January 30, 2009By Tanja Opriessnig
Porcine circovirus type 2 (PCV2) is associated with reproductive failure in pregnant female pigs; however, the role of PCV2 in semen has not been elucidated. To determine the significance of semen in...
Swine Health - General Disease
The effect of cross-fostering on the transfer of cellular and humoral maternal immunity to Mycoplasma hyopneumoniae
January 25, 2009By Thomas W. Molitor
Enzootic pneumonia resulting from Mycoplasma hyopneumoniae infections is an important disease to the US swine industry. Antibodies and immune cells specific to this agent can be detected...
Swine Health - PRRS
Development of a New Generation of Antisense Antiviral Drug against PRRSV
January 23, 2009By Yan-Jin Zhang
This project has explored a novel class of antiviral drugs to suppress PRRSV replication. These drugs were designed on the basis of PRRSV genomic sequences. Their specific binding to the virus genome...
Swine Health - PRRS
Assessing the use of biofilters and antimicrobial filters to reduce the excretion of PRRS virus into the environment
January 22, 2009By Scott Dee
As area-based PRRSV control and eradication programs move forward, the ability to minimize the risk of PRRSV-excretion into the environment from infected populations becomes important. This study...
Swine Health - General Disease
Development of a non-antibiotic selection vector for a live vaccine against PWD
January 20, 2009By Weiping Zhang
Porcine post-weaning diarrhea (PWD) continues causing substantial economic loss to swine producers. Vaccines strategy especially live attenuated vaccines could be the most effective and most...
Swine Health - PRRS
Implementation of a PRRSV Strain Database (Renewal of NPB project #06-127)
January 7, 2009By Kay S. Faaberg
The PRRSV strain database (http://prrsvdb.org) has been supported by the National Pork Board for four years. The database (PRRSVdb; 9,531 sequences) is...
Swine Health - PRRS
Development of Edible Vaccines against PRRSV: A Proof of Concept Study
December 22, 2008By Chenming (Mike) Zhang
The overall objective of this project is to develop edible vaccines to combat the devastating porcine reproductive and respiratory syndrome (PRRS) as an alternative to current MLVs. The goal is to...
Swine Health - PRRS
Identification of protective epitopes toward developing a vaccine providing broad cross-protection against various PRRS viruses
December 15, 2008By Won-Il Kim
Enormous genetic and antigenic variation impedes effective control and prevention of PRRS. Since PRRS virus vaccination is shown to be effective only against homologous or closely related viruses,...
Swine Health - PRRS
Induction of Cross-Protective Immunity Without Exposure to Live PRRSV
December 1, 2008By Luis Enjuanes
Explanation of the objectives. The development of more efficacious vaccines was one of the objectives for NPB 2007 funding. The work reported here is focused on the engineering of a...
Swine Health - PRRS
Inactivation of PRRSV using ultraviolet light
November 11, 2008By Jeffrey Zimmerman
The objective of this study was to calculate the inactivation of PRRSV by dose of UV254 in a “static” (i.e., virus-in-liquid solution) system. This study is the first step in...
