Swine Health - PRRS
Identification of protective epitopes toward developing a vaccine providing broad cross-protection against various PRRS viruses
December 15, 2008By Won-Il Kim
Enormous genetic and antigenic variation impedes effective control and prevention of PRRS. Since PRRS virus vaccination is shown to be effective only against homologous or closely related viruses,...
Swine Health - PRRS
Induction of Cross-Protective Immunity Without Exposure to Live PRRSV
December 1, 2008By Luis Enjuanes
Explanation of the objectives. The development of more efficacious vaccines was one of the objectives for NPB 2007 funding. The work reported here is focused on the engineering of a...
Swine Health - PRRS
Inactivation of PRRSV using ultraviolet light
November 11, 2008By Jeffrey Zimmerman
The objective of this study was to calculate the inactivation of PRRSV by dose of UV254 in a “static” (i.e., virus-in-liquid solution) system. This study is the first step in...
Swine Health - General Disease
Application of an Epidemiologic Survey Tool for Lawsonia intracellularis
November 3, 2008By Connie Gebhart
The objective of this study was to develop a database of L. intracellularis genotypic types from various proliferative enteropathy outbreaks. This database will provide bioinformatics data...
Swine Health - General Disease
Improving Swine Health: Enhancing Humoral and Cell-Mediated Immunity Using Novel Polymer Adjuvants
November 2, 2008By Michael Wannameuhler
As commodity markets fluctuate and producer profit margins diminish, economic loss due to infectious disease become even more important to the survivability of operations. Vaccination continues to be...
Swine Health - PRRS
The Comparative T-cell Repertoire Response in PRRSV, SIV and PCV2 Infected Piglets
October 13, 2008By John Butler
Viral infection exposes the host immune system to epitopes that are normally recognized by T cells and which leads to both cytotoxic responses against virus-infected cells and to B cells that make...
Swine Health - PRRS
Development of a simple on-site diagnostic test to detect PRRSV acute infection in boar studs
October 8, 2008By Claudia Munoz-Zanai
Because PRRSV can be transmitted through artificial insemination with semen from infected animals, boar studs are constantly being monitored for the presence of PRRSV. Current monitoring protocols...
Swine Health - General Disease
Enhanced virulence and treatment of multiple antibiotic resistant Salmonella choleraesuis in swine
October 3, 2008By Dr. Steve Carlson|Michael Kimber
Previous studies revealed that protozoa (amoebae) can augment the virulence (ability to cause disease) of certain Salmonella strains that are resistant to multiple antibiotics. This phenomenon has...
Swine Health - PRRS
B Cell Repertoire Diversification and Class Switch in PRRS
September 26, 2008By John Butler
Successful PRRSV vaccines and vaccination strategies are best employed when the host’s immune response to the pathogen is understood. Since it was generally known that PRRSV caused non-virus...
Swine Health - General Disease
Effects of high and low virulent PCV2 on activated PBMC populations
August 26, 2008By Dr. Eileen Thacker
Porcine circovirus type 2 (PCV2) associated diseases (PCVAD) have been an important cause of mortality and economic loss to the swine industry. The importance of virulence between different virus...
