Swine Health - General Disease
Development of a non-antibiotic selection vector for a live vaccine against PWD
January 20, 2009By Weiping Zhang
Porcine post-weaning diarrhea (PWD) continues causing substantial economic loss to swine producers. Vaccines strategy especially live attenuated vaccines could be the most effective and most...
Swine Health - PRRS
Implementation of a PRRSV Strain Database (Renewal of NPB project #06-127)
January 7, 2009By Kay S. Faaberg
The PRRSV strain database (http://prrsvdb.org) has been supported by the National Pork Board for four years. The database (PRRSVdb; 9,531 sequences) is...
Swine Health - PRRS
Development of Edible Vaccines against PRRSV: A Proof of Concept Study
December 22, 2008By Chenming (Mike) Zhang
The overall objective of this project is to develop edible vaccines to combat the devastating porcine reproductive and respiratory syndrome (PRRS) as an alternative to current MLVs. The goal is to...
Swine Health - PRRS
Identification of protective epitopes toward developing a vaccine providing broad cross-protection against various PRRS viruses
December 15, 2008By Won-Il Kim
Enormous genetic and antigenic variation impedes effective control and prevention of PRRS. Since PRRS virus vaccination is shown to be effective only against homologous or closely related viruses,...
Swine Health - PRRS
Induction of Cross-Protective Immunity Without Exposure to Live PRRSV
December 1, 2008By Luis Enjuanes
Explanation of the objectives. The development of more efficacious vaccines was one of the objectives for NPB 2007 funding. The work reported here is focused on the engineering of a...
Swine Health - PRRS
Inactivation of PRRSV using ultraviolet light
November 11, 2008By Jeffrey Zimmerman
The objective of this study was to calculate the inactivation of PRRSV by dose of UV254 in a “static” (i.e., virus-in-liquid solution) system. This study is the first step in...
Swine Health - General Disease
Application of an Epidemiologic Survey Tool for Lawsonia intracellularis
November 3, 2008By Connie Gebhart
The objective of this study was to develop a database of L. intracellularis genotypic types from various proliferative enteropathy outbreaks. This database will provide bioinformatics data...
Swine Health - General Disease
Improving Swine Health: Enhancing Humoral and Cell-Mediated Immunity Using Novel Polymer Adjuvants
November 2, 2008By Michael Wannameuhler
As commodity markets fluctuate and producer profit margins diminish, economic loss due to infectious disease become even more important to the survivability of operations. Vaccination continues to be...
Swine Health - PRRS
The Comparative T-cell Repertoire Response in PRRSV, SIV and PCV2 Infected Piglets
October 13, 2008By John Butler
Viral infection exposes the host immune system to epitopes that are normally recognized by T cells and which leads to both cytotoxic responses against virus-infected cells and to B cells that make...
Swine Health - PRRS
Development of a simple on-site diagnostic test to detect PRRSV acute infection in boar studs
October 8, 2008By Claudia Munoz-Zanai
Because PRRSV can be transmitted through artificial insemination with semen from infected animals, boar studs are constantly being monitored for the presence of PRRSV. Current monitoring protocols...
