Swine Health - PRRS
Induction of Cross-Protective Immunity without Exposure to Live PRRSV
December 23, 2009By Luis Enjuanes
Explanation of the objectives. The development of more efficacious vaccines was one of the objectives for NPB 2008 funding. The work reported here is focused on the engineering of a modified live...
Swine Health - General Disease
Mapping T cell epitopes in PCV2 capsid protein
December 11, 2009By Carol Wyatt
Effective circovirus vaccines require minimal numbers of conserved B and T cell epitopes that provide protective immunity. At the same time, vaccines must have the capacity to distinguish infected...
Swine Health - PRRS
Estimating the infectious dose for transmission of PRRSV by aerosol exposure
August 11, 2009By Jeffrey Zimmerman
The objective of this research was to quantify the likelihood of PRRSV transmission via aerosols as a function of exposure dose. This information is important because it reveals the process by which...
Swine Health - PRRS
Identification of Type I Interferon Antagonists of PRRSV Viral Structural Proteins
August 3, 2009By Kay S. Faaberg
PRRSV is an important swine pathogen and infections caused by this virus have not been efficiently controlled. This is in part due to the lack of knowledge about the insufficient swine immune...
Swine Health - General Disease
International collaboration to investigate the sensitivity and specificity of Mycoplasma hyopneumoniae PCR assays
July 31, 2009By Eileen Thacker
Mycoplasma hyopneumoniae (MHYO) remains a significant source of economic loss for today’s swine industry. Reliable diagnosis of this organism continues to be a challenge as demonstrated by the...
Swine Health - PRRS
Understanding the role of the regulatory immune response in porcine reproductive and respiratory syndrome virus persistence
July 30, 2009By Tanya LeRoith
This study addressed an important question in the mechanism of persistence and immune suppression by PRRSV. PRRSV persistence currently is a major problem in the field. However, the mechanism by...
Swine Health - General Disease
Is humoral immunity defective in PCV-2 infected piglets?
July 29, 2009By John Butler
Porcine multisystemic wasting syndrome (PMWS) emerged in the mid and late 1990s in herds infected with porcine circovirus type-2 (PCV-2). A growing database of field observations and experimental...
Swine Health - General Disease
Transmission of PCV2: Comparison of shedding patterns between PCV2a and PCV2b, evaluation of routes of transmission (fecal, oral, nasal, mechanical) and understanding the roles of spray-dried plasma and transport vehicles
July 22, 2009By Tanja Opriessnig
Temporal evidence correlated the emergence of PCV2b in the U.S. in 2005 with more frequent and severe porcine circovirus associated disease (PCVAD) cases. Information on the quantity and duration of...
Swine Health - General Disease
Role of Cachectic Cytokines in PMWS
July 17, 2009By Carlos Pijoan|Thomas W. Molitor
An opportunity was presented whereas sequential samples were collected in the midst of a natural outbreak of PMWS. This provided the basis to evaluate immunological and virological events in the...
Swine Health - General Disease
Evaluation of Actinobacillus pleuropneumoniae diagnostic tests using samples from naturally and experimentally infected pigs
July 6, 2009By Simone Oliveira
The objective of this study was to compare the performance of different diagnostic tests for the detection of pigs subclinically infected with Actinobacillus pleuropneumoniae. To address this...
