Swine Health - PRRS
Vaccination of pigs with alphavirus replicon particles expressing PRRSV ORF 3, 4, 5 and 6
June 21, 2010By D.L. Hank Harris
The objective of this project was to evaluate alphavirus replicon particles (RP) expressing various PRRSV proteins as vaccine candidates. Previous work has identified the minor structural...
Swine Health - PRRS
Development of a rapid, swine-specific test to simultaneously detect multiple immune proteins (cytokines) affected by PRRSV infection
June 18, 2010By Jane Christopher-Hennings
Cytokines are small secreted proteins which mediate and regulate immunity to viral infections in swine and other species. Evidence suggests that PRRSV does not induce early, effective...
Swine Health - PRRS
Sequencing, Cloning and Characterization of a 2007 Vietnam PRRSV isolate
June 17, 2010By Kay S. Faaberg
Epidemics of severe swine disease, termed “Porcine High Fever Disease (PHFD)”, continue to be reported in...
Swine Health - General Disease
Use of a production region model to evaluate biosecurity protocol efficacy for reducing the risk of porcine reproductive and respiratory syndrome virus and Mycoplasma hyopneumoniae spread between farms
June 16, 2010By Scott Dee
Porcine reproductive and respiratory syndrome virus (PRRSV) and Mycoplasma hyopneumoniae (M hyo) are economically significant pathogens of...
Swine Health - General Disease
Identification of host factors interacting with classical swine fever virus proteins: development of novel anti-viral therapeutics
June 16, 2010By Manuel Borca
During the infection of a cell, a virus gets in contact with many host proteins. These interactions between virus and host factors enable the virus the successful production of progeny and progress...
Swine Health - General Disease
Development of an improved Mycoplasma hyopneumoniae-specific ELISA
June 15, 2010By F. Chris Minion
Serology due to its low cost and ease of sample collection is the most common tool used to monitor the status of M. hyopneumoniae infection...
Swine Health - PRRS
Genetic and antigenic characterization of a recent PRRSV isolate
May 30, 2010By Tanja Opriessnig
Porcine reproductive and respiratory syndrome virus (PRRSV) NC16845 was isolated from porcine tissue submitted to the Iowa State University Veterinary Diagnostic Laboratory in 2006. The isolate...
Swine Health - General Disease
Epidemiology of porcine pestivirus and Torque teno virus in wean-to-finish pigs
May 10, 2010By Jeffrey Zimmerman
Oral fluids are inexpensive to collect. Each pen sample requires a length of cotton rope, a plastic bag, and a snap-cap plastic tube. Labor costs include the time required to place...
Swine Health - PRRS
Evaluation of adjuvants at the mucosal area for the development of innovative mucosal vaccine against PRRS
April 29, 2010By Renukaradhya Gourapura
Porcine Reproductive and Respiratory Syndrome (PRRS) is a chronic and economically important viral disease of pigs. Currently available PRRS virus (PRRSV) vaccines have been administered systemically...
Swine Health - PRRS
Identifying PRRSV structural components that activate regulatory T cells and diminish protective immunity
April 26, 2010By Tanya LeRoith
This study was designed to test the hypothesis that certain structural components of PRRSV drive the activation of regulatory T cells (Tregs). Activating these T cells would thereby diminish the...
