Swine Health - PRRS
Rational design of a broadly protective vaccine against porcine reproductive and respiratory syndrome virus
November 14, 2014By Hiep Vu
Current PRRS vaccines are not adequately effective for control and eradication of PRRS. The main limitation of the current PRRS vaccines is their sub-optimal coverage against divergent PRRSV strains...
Swine Health - PRRS
Defining a Novel Structural Component of Porcine Reproductive and Respiratory Syndrome Virus and its Role in Disease Pathogenesis
November 13, 2014By Kay S. Faaberg
The objective of this project was to characterize the makeup of nsp2, shown to be a new structural component of the PRRSV virion. Radiolabelled nsp2 protein, in the absence or presence of...
Swine Health - General Disease
Molecular Characterization and Protective/Diagnostic Application of the Capsular Polysaccharide of Haemophilus parasuis
November 5, 2014By Thomas Inzana
Haemophilus parasuis (Hps) is an important swine pathogen that can decimate a swine herd in less than 72 hours. Although this bacterium has devastating effects on pork producing facilities,...
Swine Health - PRRS
Impact of pig farm density on incidence of PRRS in a cohort of sow herds
October 1, 2014By Robert B. Morrison
This project was designed to measure the incidence of PRRS infection in a cohort of US sow herds. Additionally, it sought to conduct a risk assessment based on the density of swine farms around...
Swine Health - PRRS
Further development of an integrated mapping service to support regional control & elimination of PRRS virus
October 1, 2014By Robert B. Morrison
There are approximately 20 regional PRRS projects in the United States in various stages of progress. Each coordinator has their own approach to the challenges of mapping the region, many depending...
Swine Health - PRRS
Viral structural components that enable vaccine-induced protective immunity against contemporary high morbidity and high mortality PRRS virus
September 18, 2014By Federico A. Zuckermann
The production of interferon (IFN)- by an animal in response to a viral infection is known to be a principal determinant of the animal’s ability to fight the infection. In addition, this...
Swine Health - General Disease
Advances in Vaccine Design: Developing A Cross-conserved Influenza Vaccine for Swine
July 28, 2014By Anne De Groot
The overall goal of this project was to implement the innovative iVAX suite of immunoinformatics vaccine design tools that have been extensively validated in pre-clinical studies of human...
Swine Health - General Disease
Characterization of emerging porcine parvovirus types in the U.S. pig population
July 21, 2014By Tanja Opriessnig
A new porcine parvovirus (PPV), provisionally designated asPPV5, was identified in U.S. pigs. PPV5 is most closely related to PPV4 with overall genomic...
Swine Health - PRRS
PRRS Immunology Literature Review
July 16, 2014By Crystal Loving
PRRSV infection is a chronic infection, persisting in an animal for months. While the early stages of disease are associated with virus in the blood, that virus is eventually cleared; however,...
Swine Health - PRRS
Identification of Genetic Mutations that Confer Escape from Innate or Adaptive Host Immune Responses During PRRSV Infection In Vivo
July 15, 2014By Susan Carpenter
The major goal of the proposed study was to identify specific genetic mutations in the PRRS virus genome that confer escape from host immune responses during PRRSV infection in vivo. The study used...
